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Stability under ICH Q1A/Q1B protocols, with batch-specific CoA and third-party tested documentation, and FDA, EMA, CDSCO, FSSAI-ready dossiers

This limitation prevents us from differentiating between low initiation rates due to physician practices versus patient-related barriers such as cost, which is particularly relevant given the high out-of-pocket expenses for these medications in Poland

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Efficacy and safety profiles remained consistent in these subgroups, suggesting that semaglutide does not substantially reduce antidepressant effectiveness or worsen depression outcomes